患有的妇女的叶酸缺乏:一个范围审查
Ammar T Abdulaziz1, Nanya Hao1, Terence J O'Brien2,3
1Department of Neurology, West China Hospital, Sichuan University, Chengdu 610041, China.
Brain : a journal of neurology
|October 9, 2025
概括
叶酸缺乏症在患有的女性中很常见,与不良饮食,低叶酸 (FA) 补充剂使用和其他因素有关. 解决这一问题需要个性化的FA摄入量和更好的护理,以防止对母亲和后代的不良结果.
科学领域:
- 神经学 神经学
- 营养科学 营养科学
- 公共卫生 公共卫生
背景情况:
- 叶酸缺乏症对母亲和后代的健康构成风险.
- 患有的女性 (WWE) 是有关叶酸状况的关注人口.
- 了解WWE中不充分使用叶酸 (FA) 的原因和预测因素至关重要.
研究的目的:
- 审查关于WWE中叶酸缺乏的证据.
- 为了确定叶酸缺乏的潜在原因.
- 为了确定在WWE中不充分使用FA补充剂的预测因素.
主要方法:
- 根据PRISMA扩展指南进行范围审查.
- 在多个数据库 (Medline,Embase等) 中进行全面的文献搜索. ) 的情况.
- 从3778个审查项目中包含了105篇相关文章.
主要成果:
- 叶酸缺乏症在WWE中很普遍.
- 原因包括饮食不良,FA使用不足,遗传因素和抗发作药物.
- 低FA补充剂的使用是常见的,预测因素包括意外怀孕,低SES和缺乏咨询.
- 超过一半的WWE在怀孕前没有服用FA补充剂.
结论:
- 目前的做法需要调整,以实现WWE中足够的,个性化的叶酸水平.
- 在WWE中叶酸缺乏可能表明健康差异和健康的社会决定因素.
- 需要进一步的研究来了解 WWE 中叶酸缺乏的机制和优化干预策略.
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