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Updated: Jan 15, 2026

Oncogenic Gene Fusion Detection Using Anchored Multiplex Polymerase Chain Reaction Followed by Next Generation Sequencing
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通过针对性的下一代测序,在DNA层面检测白血病基因融合

Bin Chen1, Zhihui Gao2, Long Chen1

  • 1Sino-US Diagnostics Lab, Tianjin Enterprise Key Laboratory of AI-aided Hematopathology Diagnosis, Tianjin, China.

PloS one
|October 9, 2025
PubMed
概括

向下一代测序 (tNGS) 可以在DNA层面同时检测白血病基因突变和融合. 与传统的白血病诊断方法相比,这种新的方法提高了准确性和效率.

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相关概念视频

Next-generation Sequencing03:00

Next-generation Sequencing

The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
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