染色质可访问性和转录组分析揭示了Zygophyllum xanthoxylum中的应激反应性调节元素
Tian-Qiong Wang1, Xue-Ran Peng1, Hengbin Gao2,3
1State Key Laboratory of Herbage Improvement and Grassland Agro-Ecosystems; College of Pastoral Agriculture Science and Technology, Lanzhou University, Lanzhou 730020, P. R. China.
Plant physiology
|October 9, 2025
概括
这项研究揭示了Zygophyllum xanthoxylum如何通过打开色素来适应干旱和盐分压力,而热量则关闭它. 它确定了改善作物应激耐受性的关键监管要素.
科学领域:
- 植物生物学 植物生物学
- 表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.
- 基因组学就是基因组学.
背景情况:
- 类植物通过进化保存的 cis 调节元素 (CREs) 适应干旱的环境.
- 植物应激反应中的关键CREs和保守的非编码序列 (CNS) 基本上是未知的.
- 了解杂草植物的表观遗传调节对于提高作物弹性至关重要.
研究的目的:
- 在非生物性压力下研究Zygophyllum xanthoxylum的表观遗传调节.
- 为了识别涉及到异构体物种之间应激适应的保存非编码序列 (CNS).
- 为提高作物的耐压力提供资源.
主要方法:
- 综合的多omics方法,包括ATAC-seq和RNA-seq.
- 在热,盐和干旱压力下全基因组染色质可访问性概况.
- 五种异构植物物种的比较基因组学.
主要成果:
- 在Z. xanthoxylum中确定了2,423至77,497个可访问的染色体区域 (ACR).
- 观察到明显的染色质重塑:在盐/干旱下开放,在热下关闭.
- 发现了一种影响基因表达的ZxNF-YC10-ZxAPK1调节模块.
- 鉴定了165,896个在ACR中丰富的跨物种CNS,特别是在根中.
结论:
- Z. xanthoxylum表现出压力特定的染色质重塑策略.
- 已识别的CNS代表了对适应不利环境的关键CREs.
- 研究为开发耐压作物提供了宝贵的资源.
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