Sella Turcica三胞体21的尺寸和形状:一个CT检查
Sibel Özalp1, Mehmet Z Erdem2, Abdulaziz Yalinkiliç2
1Department of Medical Laboratory Techniques, Istanbul Medipol University School of Vocation, İstanbul.
The Journal of craniofacial surgery
|October 9, 2025
概括
与对照组相比,患有三症21 (T21) 的患者表现出较大的土角 (ST) 尺寸. 然而,ST形状在T21和对照组之间没有显著差异,表明大小受到影响,但形态却没有.
科学领域:
- 放射学 放射学是一门学科.
- 遗传学 是一个遗传学.
- 人体解剖学 解剖学 解剖学
背景情况:
- 三胞胎症21 (唐氏综合征) 是一种与各种面异常相关的遗传疾病.
- 骨 (Sella turcica,ST) 是头骨中的骨结构,在垂体腺功能中起作用,并且可以表现出形态变异.
研究的目的:
- 为了比较患有三形21 (T21) 的患者与对照组的状 (ST) 的形态特征.
- 调查T21个体和健康对照之间的ST大小和形状的潜在差异.
主要方法:
- 对45名T21患者和53名对照患者的计算机断层扫描 (CT) 图像进行了回顾性分析.
- 记录了ST长度,高度 (前部,中部,后部),宽度和直径的测量.
- 使用阿克塞尔森和坎普标准对ST形状的分类.
主要成果:
- 与对照组相比,T21患者的ST长度,前部高度,中部高度和宽度在统计学上显著增加 (P<0.001).
- 在ST直径 (P=0.098) 或后背高度 (P=0.097) 中没有发现显著差异.
- 虽然ST尺寸受到影响,但根据Axelsson和Camp分类的形状分布与T21没有显著的相关性.
结论:
- 在患有21型三症的人群中,Sella turcica的大小受到显著影响.
- 根据使用的分类,Sella turcica的形状似乎与三发性病21无关.
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