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Updated: Jan 15, 2026

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

Published on: October 26, 2015

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仿制同型基因GDF15蛋白质的单环合体的设计,以抑制GDF15-GFRaL-RET复杂细胞信号传递

Anaïs F M Noisier, Jenny Sandmark, Fredrik Edfeldt

  • 1BicycleTx Limited, Portway Building, Granta Park, Cambridge CB21 6GS, U.K.

Journal of medicinal chemistry
|October 9, 2025
PubMed
概括

研究人员开发了针对GDF15-GFRaL-RET通路的新型抑制剂. 这些自行车分子模仿GDF15的GDF15.

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Development of a Backbone Cyclic Peptide Library as Potential Antiparasitic Therapeutics Using Microwave Irradiation08:48

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