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Updated: Jan 15, 2026

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高葡萄糖微环境通过O-GlcNAcylation在口腔状细胞癌中加速恶性进展

Zhuang Zhu1, Wenhao Ren2, Xiaohan Yan1

  • 1Department of Oral and Maxillofacial Reconstruction, The Affiliated Hospital of Qingdao University, Qingdao, China; School of Stomatology, Qingdao University, Qingdao, China; Department of Oral and Maxillofacial Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China.

International dental journal
|October 9, 2025
PubMed
概括

糖尿病通过O-GlcNAcylation促进口腔癌的进展. 在高葡萄糖环境中抑制O-GlcNAcylation可以减少口腔状细胞癌 (OSCC) 细胞增殖和转移,为糖尿病OSCC患者提供新的治疗途径.

关键词:
糖尿病是一种糖尿病.高葡萄糖的微环境中的高葡萄糖.这是一种O-GlcNAcylation.口腔状细胞癌的癌症.在PI3K/AKT/mTOR路径中.

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