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Updated: Jan 15, 2026

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells
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Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

Published on: June 7, 2019

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在B16-F10细胞中激发黑色素的含义,对乌比奎丁-蛋白酶体系统的影响

Dainesy Santos Martins1, Marilene Demasi2, Daniel de Lima Bellan3

  • 1Postgraduate Program in Biochemistry Sciences, Department of Biochemistry and Molecular Biology, Federal University of Paraná (UFPR), Curitiba, PR, Brazil.

Biochemical and biophysical research communications
|October 9, 2025
PubMed
概括

耐BTZ等蛋白酶体抑制剂的黑色素瘤细胞可以通过向泛化过程来克服. 使用PYZD-4409抑制E1酶有效诱导黑色素瘤细胞的亡,提供了一个有前途的治疗策略.

关键词:
博尔特佐米比 (Bortezomib) 是一种可怕的药物.黑色素是黑色素的一种.黑色素瘤是一种黑色素瘤.蛋白质酶体是一种蛋白质酶体.乌比奎丁是一种存在的药物.

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