基于消化动力学,微生物组和代谢学分析的化粉的消化和发酵特性
Tong Wang1, Chang Liu1, Rongrong Ma1
1State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, Wuxi 214122, China.
乙化粉 (ES) 修改了肠道微生物群,减少了病原体并增强了氨基酸代谢. 它的分子结构影响这些有益的肠道健康效应.
科学领域:
- 食品科学 食品科学 食品科学
- 微生物学 微生物学
- 营养生物化学 营养生物化学
背景情况:
- 耐性粉,特别是精化粉 (ES),在食品工业中广泛使用.
- 了解ES对消化和肠道微生物群的影响对于其应用至关重要.
研究的目的:
- 为了研究不同替代组的化粉 (ES) 的消化和发酵特性.
- 阐明ES对肠道微生物群组成和代谢功能的影响.
主要方法:
- 使用了体外消化动力学和发酵试验.
- 进行了微生物组和代谢学分析.
- 结构方程建模用于将分子特性与生物效应相关联.
主要成果:
- 雌性化减缓了粉的消化速度,并改变了它的结构性质.
- ES显著降低了肠道微生物群中的机会性病原体的丰富性.
- ES增强了微生物的酸盐代谢和与氨基酸相关的途径,具有特定的酶过度表达 ([EC: 1.2.4.1], [EC: 2.3.1.12]).
结论:
- 雌性化粉调节肠道微生物群的组成和功能.
- ES的分子量分布是影响肠道微生物群和宿主新陈代谢的关键因素.
- ES显示出作为改善肠道健康的益生菌成分的潜力.
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