hs-CRP-triglyceride葡萄糖指数与阻塞性睡眠呼吸暂停之间的关联:NHANES 2015-2018年的研究
1Department of Anesthesiology, The Fifth Affiliated Hospital of Sun Yat-sen University, 52 Meihua East Road, Zhuhai, Guangdong, 519000, China.
Respiratory medicine
|October 9, 2025
概括
糖分指数 (CTI) 与阻塞性睡眠呼吸暂停 (OSA) 的更高风险有关. 升高的CTI水平可以作为一种潜在的生物标志物,用于识别患有OSA风险的个体.
科学领域:
- 代谢综合征是代谢综合征的一种.
- 睡眠医学 睡眠医学
- 心血管健康 心血管健康
背景情况:
- 反应性C蛋白-三甘油糖指数 (CTI) 结合了胰岛素抵抗和炎症.
- CTI和阻塞性睡眠呼吸暂停 (OSA) 风险之间的关联尚未得到充分证实.
- 调查CTI在OSA中的作用对于了解代谢和炎症与睡眠障碍的联系至关重要.
研究的目的:
- 检查CTI与患上OSA的风险之间的关联.
- 评估CTI作为OSA的潜在生物标志物.
- 用国家健康和营养检查调查 (NHANES) 的数据分析这种关系.
主要方法:
- 从2015-2018年NHANES数据库中对3512名参与者的横截面分析.
- 多变量逻辑回归模型来评估CTI-OSA的关联.
- 限制立方线,ROC和子组分析,以进行可靠的评估.
主要成果:
- 在CTI和OSA风险之间发现了显著的积极关联 (OR=1.14每单位).
- 最高的CTI四分位数显示,与最低的相比,OSA风险增加了1.35倍.
- 与hs-CRP和TyG.相比,CTI对OSA表现出更好的区分能力.
结论:
- 升高的CTI水平与增加的OSA风险相关.
- 在OSA查和风险评估中,CTI显示出作为一种有价值的生物标志物的潜力.
- 这一发现突显了代谢健康,炎症和睡眠呼吸暂停之间的相互作用.
更多相关视频
04:53Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach
Published on: October 18, 2024
1.4K
07:22Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes
Published on: March 7, 2025
717
相关概念视频
Sleep Apnea
479
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
The condition is more prevalent among...
479
Substance Use Disorders Affecting Sleep
400
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
400
Correlations
35.8K
Correlation means that there is a relationship between two or more variables (such as ice cream consumption and crime), but this relationship does not necessarily imply cause and effect. When two variables are correlated, it simply means that as one variable changes, so does the other. We can measure correlation by calculating a statistic known as a correlation coefficient. A correlation coefficient is a number from -1 to +1 that indicates the strength and direction of the relationship between...
35.8K
Coronary Artery Disease I: Introduction
878
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
878
