改变高影响性慢性疼痛风险分布:人口层面干预的目标
Marcus Beasley1, Gary J Macfarlane1, 1
1Aberdeen Centre for Arthritis and Musculoskeletal Health (Epidemiology Group), University of Aberdeen, UK.
The journal of pain
|October 9, 2025
概括
增加体力活动和降低体重指数 (BMI) 可以降低高影响性慢性疼痛的患病率. 促进健康体重和活动的人口层面干预措施可能会减少慢性疼痛负担.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 疼痛管理 疼痛管理
背景情况:
- 高影响性慢性疼痛显著降低了生活质量,并使医疗保健系统受到压力.
- 针对可修改风险因素的人口层面策略对于减轻慢性疼痛影响至关重要.
研究的目的:
- 通过全人口增加体力活动和降低身体质量指数 (BMI) 来估计高影响性慢性疼痛患病率的潜在降低.
- 通过量化生活方式修改对慢性疼痛的影响,为公共卫生战略提供信息.
主要方法:
- 使用来自166,926名参与者的英国生物库数据进行横截面分析.
- 人口干预模型,以评估身体活动和BMI变化对慢性疼痛患病率的影响.
- 通过慢性疼痛和生活质量下降来定义的高影响性慢性疼痛 (Euroqol EQ-5D-5L).
主要成果:
- 每周增加2天,每次20分钟的剧烈体力活动,与患病率从18.1%降至16.7% (调整后) 的降低有关.
- 体重指数下降7%与患病率从18.9%降至16.8% (未调整) 和17.5% (完全调整).
- 观察到的效应在各种人口学子组中是一致的.
结论:
- 人口范围内的身体活动和BMI的转变可以显著降低高影响性慢性疼痛的患病率.
- 研究结果支持以环境和社会健康决定因素为重点的公共卫生干预措施,用于慢性疼痛管理.
- 在人口层面上促进体育活动和健康体重是解决慢性疼痛负担的可行策略.
相关概念视频
01:25Analgesia and Pain Management
1.5K
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
1.5K
01:29Chronic Pancreatitis II: Collaborative Care
311
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Assessment:
311
01:23Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
406
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
406
01:25Strategies for Assessing and Addressing Confounding
360
Confounding is a critical issue in epidemiological studies, often leading to misleading conclusions about associations between exposures and outcomes. It occurs when the relationship between the exposure and the outcome is mixed with the effects of other factors that influence the outcome. Given that, addressing confounding is of high importance for drawing accurate inferences in research.
Confounding can be addressed at both the design phase of a study and through analytical methods after data...
Confounding can be addressed at both the design phase of a study and through analytical methods after data...
360