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Updated: Jan 15, 2026

Isolation and Characterization of Primary Rat Valve Interstitial Cells: A New Model to Study Aortic Valve Calcification
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内皮腺素受体2A损失通过阻断CREB1-SNAI1驱动的EndMT来缓解糖尿病血管化

Yaqi Zhou1, Dingwei Zhao2, Qian Ma3

  • 1State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, China; Department of Physiology, Research Center of Basic Integrative Medicine, School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, 232 Waihuan East Road, University Town, Guangzhou 510006, China; Vascular Biology Center, Department of Cellular Biology and Anatomy, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.

Pharmacological research
|October 9, 2025
PubMed
概括

无活化内皮腺受体A2A (ADORA2A) 通过阻断内皮到介质细胞转换 (EndMT) 来降低糖尿病患者的血管化 (VC). 这表明ADORA2A抗剂可以治疗糖尿病并发症.

关键词:
腺氨酸受体2 A 腺氨酸受体2 A在CREB1中,CREB1是指CREB1,CREB1是指CREB1,CREB1是指CREB1.糖尿病是一种糖尿病.内皮细胞到介质细胞的过渡.在SNAI1上,你会看到SNAI1.血管化是因为血管化.

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