针对PSMA的放射性药物的全球研究格局:为期二十年的多维文献识别分析
Ze-Lin Yang1, Su-Qin Xu2, Cheng-Lu Huang3
1Department of Thoracic Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, 710000, China.
Japanese journal of radiology
|October 9, 2025
概括
本文献分析绘制了针对前列腺特异性膜抗原 (PSMA) 向放射性药物的全球研究. 关键发现突出显示了PSMA治疗术的增长,并确定了新兴的人工智能驱动和组合疗法研究方向.
科学领域:
- 核医学和分子成像技术
- 在瘤学瘤学.
- 放射性药物科学 放射性药物科学
背景情况:
- 前列腺特异性膜抗原 (PSMA) 向的放射性药物已经改变了前列腺癌的治疗方法.
- 需要对全球研究格局进行全面的文献计量分析,以了解趋势并指导未来的发展.
- 这项研究解决了PSMA放射性药物研究缺乏整体概述的问题.
研究的目的:
- 对针对PSMA的放射性药物进行全球研究进行全面的文献计量分析.
- 绘制该领域的发展图,识别关键贡献者,并确定新兴研究方向.
- 为资源分配提供信息,并指导PSMA天文学的未来进展.
主要方法:
- 从科学网络核心收藏中对3,249篇出版物 (2005-2025) 的图书统计分析.
- 使用VOSviewer,CiteSpace和biblioshiny R包进行数据可视化和分析.
- 包括有关国家,机构,研究人员,期刊和引用模式的数据.
主要成果:
- 德国领先于研究成果;慕尼黑理工大学是最有影响力的机构.
- 欧洲核医学杂志和分子成像学杂志以及核医学杂志是关键出版物.
- 研究热点包括Ga-PSMA-PET/CT,基于Lu的治疗和AI创新,在2018年后有显著增长.
- 马蒂亚斯·艾伯和A. Afshar-Oromieh被认为是非常有影响力的研究人员.
结论:
- 该分析概述了PSMA放射性药物研究的演变.
- 确定的新兴研究趋势包括人工智能增强的治疗术,免疫疗法组合和生物标志物引导的分层.
- 调查结果为PSMA神经科学领域的未来精确瘤学发展提供了洞察力.
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