在活跃的1型糖尿病患者中,两种运动后循环细胞因子的模式
María Herranz-López1,2, Rodrigo Martín-San Agustín1, Mariló Olivares-Vicente3
1Clinimetry and Technological Development in Therapeutic Exercise Research Group (CLIDET), Department of Physiotherapy, University of Valencia, Valencia, 46010, Spain.
高强度间歇训练 (HIIT) 可能是1型糖尿病 (T1DM) 患者有氧运动的可行替代方案,影响炎症类细胞因子. 适度强度间歇运动仍然是T1DM管理的安全选择.
科学领域:
- 运动生理学 运动生理学
- 免疫学 免疫学 免疫学
- 内分泌学 在内分泌学.
背景情况:
- 有氧训练对1型糖尿病 (T1DM) 有好处,但可以单调.
- 高强度间歇训练 (HIIT) 为T1DM患者提供了一个有吸引力的替代方案.
- 了解运动对炎症性细胞因子的影响对于T1DM管理至关重要.
研究的目的:
- 为了比较有氧与HIIT对T1DM患者炎症性细胞因子调节的影响.
- 为了研究单次有氧和HIIT会的细胞因子反应.
- 在接受HIIT计划的T1DM患者中探索长期的细胞因子变化.
主要方法:
- 招募了26名男性T1DM患者 (18-40岁) 接受控制的糖化血红蛋白.
- 参与者接受了单独的有氧和HIIT课程,在运动前和运动后收集血液样本.
- 使用LUMINEX技术测量细胞因子水平;国际体力活动问卷 (IPAQ) 分类强度.
主要成果:
- 对于IPAQ水平2和3,有氧运动对促炎性细胞因子 (IL-1β,IL-6,IL-7,IL-8,IL-17A,TNF-α,IFN-γ) 没有显著变化.
- 只有抗炎性细胞因子IL-2在有氧运动后在IPAQ:3参与者中显著增加.
- HIIT引发了类似的模式,12周的计划显示IL-7,IL-8,TNF-α和抗炎细胞因子IL-22的增加.
结论:
- 在T1DM患者中,HIIT似乎促进了某些促炎细胞因子的存在.
- 像IL-22这样的细胞因子的抗炎作用需要考虑补偿作用.
- 适度强度间歇运动计划目前被推为T1DM患者的安全选择.
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