设备测量体育活动,2型糖尿病和未来10年的预期寿命之间的关联:一项前性的纵向研究
Ziqiang Lin1, Jiade Chen1, Yutai Cai1
1Department of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou, Guangdong, China.
BMC public health
|October 9, 2025
概括
身体活动中介于2型糖尿病和死亡风险. 将久坐时间重新分配到中度至剧烈的体力活动可以使2型糖尿病患者的预期寿命增加一年以上.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 代谢疾病 代谢疾病
背景情况:
- 24小时身体活动在2型糖尿病和死亡率之间的联系中的作用仍然不清楚.
- 关于改变日常活动模式如何影响2型糖尿病患者的预期寿命的研究有限.
研究的目的:
- 研究24小时体育活动对2型糖尿病和死亡率之间的关联的调解效应.
- 确定不同日常活动之间重新分配时间对2型糖尿病患者的预期寿命的影响.
主要方法:
- 利用了来自103,359名英国生物库参与者的加速度计数据 (平均年龄57岁).
- 采用组合调解考克斯模型来分析身体活动的调解效应.
- 应用队列寿命表方法来估计从活动替代10年预期寿命的变化.
主要成果:
- 糖尿病与静坐行为 (SB) 的增加以及中度至剧烈体力活动 (MVPA) 和轻强体力活动 (LPA) 的降低相关,增加死亡风险.
- 身体活动占糖尿病对死亡率总影响的41.9% (HR=1.27).
- 将SB替换为MVPA可以在10年内获得高达1.32年的预期寿命.
结论:
- 24小时的体力活动模式似乎调解了2型糖尿病和死亡率之间的关系.
- 在2型糖尿病患者中鼓励MVPA和减少SB可能会在未来十年提高预期寿命.
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