乳糖菌对办公室工作者的焦虑和睡眠困难的影响:双盲随机对照试验
Shu-I Wu1,2, Kai-Liang Kao3, Chen-Ju Lin4
1Department of Medicine, MacKay Medical College, New Taipei City, Taiwan. t140@mmu.edu.tw.
Annals of general psychiatry
|October 10, 2025
概括
活乳酸酶ibacillus paracasei PS23 (PS23) 补充剂改善了压力高的办公室工作人员的睡眠质量,并减少了焦虑. 这种益生菌可能是一个有前途的干预措施,用于管理工作场所的压力症状.
科学领域:
- 微生物学 微生物学
- 心理学 心理学 心理学
- 人类营养人类营养
背景情况:
- 在一般人群中,睡眠障碍和压力的患病率增加.
- 失眠和不良的压力管理与不良的身体和心理健康结果有关.
- 以前的研究表明,经过热处理的L. paracasei PS23 (PS23) 可以缓解压力较大的个体的焦虑.
研究的目的:
- 研究活体L. paracaseiPS23 (PS23) 对办公室工作者的睡眠质量,焦虑和压力的影响.
- 探索现场PS23作为对工作场所相关压力的干预措施的潜力.
- 评估压力标志物和抗氧化剂水平的变化.
主要方法:
- 一项为期六周的随机对照试验,涉及有中度至高感知压力的办公室工作者 (20-65岁).
- 干预组每天接受活体L. paracaseiPS23 (20亿CFU);对照组接受安慰剂.
- 在基线和试验结束时评估压力,焦虑,睡眠质量,疲劳,抑郁,生活质量,唾液压力标志物和抗氧化剂水平.
主要成果:
- 在完成试验的45名参与者中观察到高服从率 (>80%).
- 与安慰剂相比,PS23组在整体失眠症状 (p=0.011) 中呈现出统计学上显著的改善.
- 在PS23组中,睡眠延迟显著减少 (p=0.045),睡眠维持改善 (p=0.002),特征焦虑减少 (p=0.044).
结论:
- 实体L. paracaseiPS23 (PS23) 补充剂显示有潜力改善压力较大的办公室工作者的睡眠质量.
- 活体PS23可以有效地降低经历过高压力的个体中的焦虑水平.
- 这项试点研究表明L. paracasei PS23作为一个有希望的益生菌干预工作场所压力管理.
关键词:
焦虑 焦虑是一种焦虑.乳酸酶ibacillus paracasei PS2323 乳酸酶ibacillus paracasei PS23 乳酸酶ibacillus paracasei 乳酸酶ibacillus paracasei PS23 乳酸酶ibacillus paracasei 乳酸酶ibacillus paracasei 乳酸酶ibacillus paracasei PS23 乳酸酶ibacillus paracasei 乳酸酶ibacillus paracasei 乳酸酶ibacillus paracasei 乳酸酶ibacillus paracasei 乳酸酶办公室工作者办公室工作者益生菌是一种益生菌.睡眠 睡眠 睡眠 睡眠更多相关视频
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