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Updated: Jan 15, 2026

An Adoptive Transfer Model of Rheumatoid Arthritis in Mice
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编辑RNA的酶ADAR1通过调节纤维细胞样同胞细胞衍生的外体循环FTO减轻类风湿性关节炎

Yuxuan Fang, Nan Xu, Jiacheng Shen

    International archives of allergy and immunology
    |October 10, 2025
    PubMed
    概括

    在类风湿性关节炎 (RA) 中,作用于RNA 1 (ADAR1) 的腺氨酸脱氨酶的下调. 在RA中恢复ADAR1水平可能通过调节circFTO并减少疾病严重程度来提供治疗策略.

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