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在氧化压力期间的生化和生理反应:跨物种的视角

Dharmsheel Shrivastav¹, Juhi Mishra², Varun Kumar Sharma¹

¹Department of Biotechnology and Microbiology, School of Sciences, Noida International University-NIU, Greater Noida, India.

Rejuvenation research

|October 10, 2025

概括

氧化应激影响所有动物,从无脊椎动物到脊椎动物,由于反应性氧物种 (ROS) 和抗氧化剂的不平衡. 了解这些保存和独特的压力路径是动物健康和适应的关键.

科学领域:

动物学动物学
环境毒理学环境毒理学
细胞生物学细胞生物学

背景情况:

氧化应激源于活性氧物种 (ROS) 和抗氧化剂之间的不平衡,影响所有动物种类.
环境污染物,重金属,杀虫剂和疾病等内源因素会增加ROS的产生,损害细胞组件.
这种细胞损伤损害了各种动物群体的完整性和功能.

研究的目的:

综合比较无脊椎动物和脊椎动物中氧化应激的影响和途径.
阐明动物进化过程中氧化应激反应的共同和独特机制.
突出动物生理学和适应性中氧化还原平衡的普遍作用.

主要方法:

综合证据综合从图形表示和生物途径.
对无脊椎动物和脊椎动物群体中氧化应激影响的比较分析.
识别保存的分子机制和防御策略.

主要成果:

氧化应激是影响无脊椎动物和脊椎动物的根本挑战.
保存的机制包括脂质过氧化,芬顿化学和防御酶的上调.
观察到明显的压力路径,但反应对恒温和生存至关重要.

结论:

氧化应激反应在整个动物进化过程中都保持不变,尽管存在差异.
氧化还原平衡对于细胞平衡,炎症调节和所有动物的生存至关重要.
研究结果提供了关于压力生理学的见解,以及减轻氧化损伤的潜在目标.

关键词:

抗氧化剂抗氧化剂是一种抗氧化剂.无脊椎动物是一种无脊椎动物.分子路径的分子路径.氧化应激是一种氧化应激.有脊椎动物的脊椎动物.

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