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在儿科心脏移植中免疫风险分层的综合分子不匹配得分

Mitchell A Ellison1, Qingyong Xu2, Adriana Zeevi2

  • 1University of Pittsburgh Medical Center (UPMC).

Current opinion in organ transplantation
|October 10, 2025
PubMed
概括

新的HLA分子不匹配算法提高了对儿科心脏移植中de-novo供体特异抗体 (DSA) 和拒绝的预测. 将HLAMatchmaker或HLA-EMMA与PIRCHE-II结合起来,可以提供更细致的风险评估,以获得更好的患者结果.

关键词:
HLA分子不匹配的情况通过抗体介导的排斥.在 de-novo 供体特异性抗体.免疫抑制是一种免疫抑制.儿科心脏移植手术

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Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
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