体重指数和精神障碍:一项丹麦队列研究
Sigrid Bjerge Gribsholt1,2,3, Kristina Laugesen1,4, Oleguer Plana-Ripoll1,5
1Department of Clinical Epidemiology, Center for Population Medicine, Aarhus University and Aarhus University Hospital, Aarhus, Denmark.
Diabetes, obesity & metabolism
|October 10, 2025
概括
体重不足和肥胖都与各种心理健康状况的风险增加有关. 这项研究强调了监测身体质量指数 (BMI) 异常的人的心理健康的重要性.
科学领域:
- 公共卫生 公共卫生
- 精神病学是一个精神病学.
- 流行病学 流行病学
背景情况:
- 低体重和高体重是全球重要的健康问题.
- 体重可能与特定的心理健康障碍有关.
研究的目的:
- 调查身体质量指数 (BMI) 和特定精神障碍之间的关联.
- 分析BMI与精神分裂症,情绪障碍,焦虑和饮食障碍等疾病的联系.
主要方法:
- 丹麦基于人口的队列研究包括290,468名18-79岁的参与者.
- 身体质量指数 (BMI) 被分析为连续变量 (立方脊柱) 和分类变量 (体重不足,正常体重,超重,肥胖).
- 使用因果特异的考克斯比例危险回归来估计精神障碍的发病率和调整后的危险比率,平均随访时间为5年.
主要成果:
- 在BMI和精神分裂症,情绪障碍,焦虑,压力相关障碍,体形障碍,饮食障碍和人格障碍之间观察到U形关联.
- 低BMI,但不是高BMI,与有机和物质使用障碍有关.
- 这些关联在女性中通常比男性更强,并且随着年龄的增长而减少.
结论:
- 体重不足和肥胖都与精神障碍的风险增加有关,具体情况取决于不同的模式.
- 这些发现强调需要监测体重不足和肥胖的人的心理健康.
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