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Updated: Jun 28, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
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合成,生物评价和对接分析新型本齐米达-三醇混合物作为潜在的抗癌剂

Amir Shervin Shokouhi Asl1, Sara Ranjbar2, Mohammad Hosein Sayahi3

  • 1Department of Medicinal Chemistry, School of Pharmacy, Iran University of Medical Sciences Tehran Iran.

RSC advances
|October 10, 2025
PubMed
概括

新型的西米达-三乙胺混合物显示出强烈的抗癌活性. 衍生物9f有效抑制癌细胞生长并诱导细胞亡,显示出作为选择性抗癌剂的承诺.

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Drug discovery is a multifaceted process involving extensive screening, testing, and optimization of lead compounds to identify potential new drugs for therapeutic use. It combines several approaches, including screening large numbers of natural products, chemical modification of known active molecules, identification of new drug targets, and rational design based on biological mechanisms and drug-receptor structure. These approaches are carried out in both academic research laboratories and...