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Updated: Jan 15, 2026

Imaging the Intracellular Trafficking of APP with Photoactivatable GFP
07:55

Imaging the Intracellular Trafficking of APP with Photoactivatable GFP

Published on: October 17, 2015

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β-粉样蛋白通过Na,K-ATPase-Src激酶正反循环影响β-粉样蛋白前体蛋白的含量和贩运

Irina Y Petrushanko1, Denis R Lisitskii1, Filipp A Filonov1

  • 1Engelhardt Institute of Molecular Biology Russian Academy of Sciences, Moscow, Russia.

Frontiers in pharmacology
|October 10, 2025
PubMed
概括

β-粉样蛋白 (Aβ) 通过增加神经元中的β-粉样蛋白前体蛋白 (APP) 来加速阿尔茨海默氏症的病理. 像ouabain这样的心性类固醇 (CTS) 可能会抵消这种效果,提供治疗潜力.

关键词:
这就是为什么APP APP APP APP.在 APP 贩运 APP 贩运.这就是Na,K-ATPase.这就是Src 激酶.贝塔氨基化物-贝塔氨基化物乌阿巴林,就是这样.

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