语音和语言特征作为记忆诊所人口中神经精神病症状的指标
Zampeta-Sofia Alexopoulou1, Elisa Mallick2, Johannes Tröger2
1CoBTeK (Cognition-Behaviour-Technology) Research Lab Université Côte d'Azur Nice France.
Alzheimer's & dementia (Amsterdam, Netherlands)
|October 10, 2025
概括
语音分析可以检测神经认知障碍 (NCD) 中的神经心理症状 (NPS). 语音不稳定与抑郁相关,而动荡与轻度认知障碍和主观认知衰退患者的语音暂停有关.
科学领域:
- 神经学 神经学
- 语音语言病理学 语言病理学
背景情况:
- 神经心理症状 (NPS) 是神经认知障碍 (NCD) 的早期指标.
- 语音改变可以反映非传染性疾病的认知和行为变化,有助于诊断和监测.
- 这项研究研究了自动语音/语言特征与NPS严重程度之间的关系.
研究的目的:
- 检查自动提取的语音和语言特征与NPS严重程度之间的关联.
- 探索语音分析作为评估NCD中NPS的客观工具的实用性.
主要方法:
- 37名主观认知衰退和20名轻度认知障碍的参与者接受了自由言论任务.
- 使用老年抑郁症尺度和神经精神病 inventory 评估NPS.
- 提取了声学和语言特征,并与临床尺度相关联,并根据共变量进行调整.
主要成果:
- 在语音特征和NPS之间发现了显著的相关性.
- 抑郁与局部动相关 (r=0.38,p<0.001).
- 兴奋与总休息时间正相关 (r=0.32,p<0.027).
- 焦虑与词汇多样性指标有负面关联.
结论:
- 语音分析是评估非传染性疾病中的NPS的一个有希望的工具.
- 客观语音标记可以帮助评估主观认知衰退和轻度认知障碍患者的NPS.
相关概念视频
01:30Negative and Cognitive Symptoms of Schizophrenia
458
Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
458
01:30Positive Symptoms of Schizophrenia: Hallucinations and Delusions
544
Schizophrenia is a complex mental health disorder that can manifest with various positive symptoms, including thought, movement, and behavior disorders. These symptoms significantly disrupt cognitive and motor functions, leading to profound effects on an individual's ability to engage with the world.
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes...
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes...
544
01:27Language and Cognition
711
Language serves as a bridge between ideas and communication, influencing how individuals perceive and interact with the world. Psychologists have long debated whether language shapes thought or vice versa. This discussion gained grip with Edward Sapir and Benjamin Lee Whorf in the 1940s, who proposed that language determines thought, a concept known as linguistic determinism. They suggested that the vocabulary and structure of a language influence how its speakers think and perceive reality.
711
01:10Higher Mental Functions of the Brain: Language
3.4K
Language is a system of communication that allows the expression of thoughts, ideas, and feelings. The brain processes language in both hemispheres.
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...
3.4K
01:19Autism Spectrum Disorder
973
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
973
01:26Positive Symptoms Schizophrenia: Hallucinations and Delusions
467
Schizophrenia is a complex psychiatric disorder characterized by a range of symptoms that significantly impact cognition, behavior, and emotional regulation. Among these, the positive symptoms stand out as they involve the addition or exaggeration of normal mental functions, deviating markedly from typical behavior and perception. Hallucinations and delusions are prominent positive symptoms, each profoundly affecting the individual's experience of reality.
Hallucinations
Hallucinations in...
Hallucinations
Hallucinations in...
467