用蓝色激光成像进行放大内镜的诊断有效性,用于喉回流的喉回流
Rong Wang1,2, Min Yu1,3, Chaoyuan Chen2
1Fuzong Clinical Medical College of Fujian Medical University, Fuzhou, China.
Frontiers in medicine
|October 10, 2025
概括
使用蓝色激光成像 (ME-BLI) 的放大内镜显示出诊断喉回流 (LPR) 的前景. 这种技术具有很高的灵敏度和与既定临床标准的良好一致性,有可能提高LPR的诊断准确性.
科学领域:
- 胃肠病学 胃肠病学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 医疗成像医学成像
背景情况:
- 喉回流 (LPR) 提出了诊断方面的挑战.
- 准确诊断LPR对于有效管理至关重要.
- 当前的诊断方法可能在识别微妙的喉变化方面存在局限性.
研究的目的:
- 评估蓝色激光成像 (ME-BLI) 的放大内镜对于喉回流 (LPR) 的诊断效用.
- 将ME-BLI的诊断性能与已建立的临床参考标准 (RSI和RFS) 进行比较.
主要方法:
- 纳入了106名患有LPR相关症状的患者.
- 在所有参与者身上进行了ME-BLI.
- 根据ME-BLI,患者根据喉外观和皮质内乳头毛细管环 (IPCLs) 进行分级,分级3-4定义为LPR阳性.
主要成果:
- 与RSI/RFS标准相比,ME-BLI在LPR诊断方面表现出高灵敏度 (89.71%) 和良好的特异性 (73.68%).
- 该技术与RSI/RFS诊断有很好的一致性 (卡帕=0.65).
- 对于ME-BLI分级 (ICC = 0.858) 观察者之间有很好的一致性.
结论:
- ME-BLI显示了提高LPR的诊断准确性的潜力.
- 在LPR诊断中在ME-BLI辅助下观察到的特征性喉表现.
- 建议进行进一步的验证研究,以确认ME-BLI在LPR诊断中的作用.
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