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能量压力诱导的PKCζ S-Glutathionylation对于LKB1细胞质转位和AMPK激活至关重要

Junjie Fei1, Shuhan Yu1, Mingzhe Xu1

  • 1Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, Sichuan 610064, China.

Life metabolism
|October 10, 2025
PubMed
概括

能量压力通过活性氧物种 (ROS) 激活AMP激活蛋白激酶 (AMPK),促进蛋白激酶C zeta (PKCζ) 核进口. 这促进了肝激酶B1 (LKB1) 的细胞质转移和AMPK激活.

关键词:
这就是AMPKK.一个LKB1一个LKB1在PKCζζζ这就是ROSOS ROS.在S-Glutathionylation的过程中,S-Glutathionylation的作用是什么?能量压力 能量压力

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