在临床实践中对白风的评估:在专家中进行的横截面调查
Jolien Duponselle1, Marlide R Jukema2, Albert Wolkerstorfer2
1Department of Dermatology, Ghent University Hospital, Ghent, Belgium.
The Journal of dermatological treatment
|October 10, 2025
概括
Vitiligo 专家在临床实践中评估疾病演变和治疗耐受性等结果. 本研究确定了关键评估,以制定一个标准化的核心结果集,以更好地管理白风.
科学领域:
- 皮肤病学 皮肤病学
- 临床研究 临床研究
- 患者为中心的结果.
背景情况:
- 以患者为中心的结果对于最佳的白风护理至关重要.
- 对于白风试验,有一个核心领域集 (CDS),但对于临床实践来说,没有相当的东西阻碍了一致的管理.
- 不一致的结果评估使得有效的白风病管理变得复杂.
研究的目的:
- 调查白风专家在临床实践中评估的结果和特征.
- 为开发临床实践的核心结果集 (COS) 提供信息.
- 确定临床实践中的关键结果测量工具.
主要方法:
- 在六大洲的31位白风专家中进行了一项横截面调查.
- 调查包括28个预定义的结果和特征,并为专家提出的其他项目提供选择.
- 被70%以上的参与者评估的结果被认为是"一般评估".
主要成果:
- 六个结果和21个特征被白风专家普遍评估.
- 最常见的评估结果包括白风的演变,治疗耐受性/不良事件,疾病活性和白风程度.
- 鉴定了当前临床实践评估与现有的临床试验标准之间的差异.
结论:
- 目前的白风专家评估与试验的CDS相比,显示了相似之处和差异.
- 这些发现是制定临床实践COS的关键准备步骤.
- 未来的COS开发将涉及专家和非专家皮肤科医生,以及患者.
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