青少年心血管风险轨迹和晚年母亲发病率
Katharine J McCarthy1,2, Annabelle Ng1, Natalie A Boychuk3
1Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, New York.
JAMA network open
|October 10, 2025
概括
青春期和年轻成年期心血管健康不佳与更高的妊娠糖尿病和妊娠高血压疾病风险有关. 在生命早期保持最佳的心血管健康可以显著降低这些风险.
科学领域:
- 心血管健康 心血管健康
- 产科 产科 产科 产科 产科
- 公共卫生 公共卫生
背景情况:
- 怀孕期间与心血管相关的发病率是一个越来越大的健康挑战.
- 了解青少年和年轻人的心血管健康对怀孕结果的长期影响对于预防至关重要.
研究的目的:
- 调查青春期和年轻成年期心血管风险与生命后期不良怀孕结果之间的联系.
- 确定早期干预的潜在目标,以改善母亲和胎儿的健康.
主要方法:
- 一项队列研究利用了来自全国青少年和成人健康纵向研究的数据.
- 心血管健康 (CVH) 风险使用适应的生命必需品8级评估.
- 孕期糖尿病 (GD) 和妊娠高血压障碍 (HDP) 是主要的结局,使用对共变量调整的逻辑-二项式回归来分析.
主要成果:
- 患有不良青少年CVH的参与者与最佳CVH (4.7%) 的参与者相比,GD发病率明显高 (28.5%).
- 青少年CVH不良与未来GD (ARR 2.01) 和HDP (ARR 1.22) 的风险增加有关.
- 改善从青春期到年轻成人时期的CVH显示了GD发病率的潜在减少.
结论:
- 青春期和年轻成年期心血管健康不佳与妊娠糖尿病的风险增加有关.
- 在青春期实现最佳的心血管健康可能是减轻成人妊娠糖尿病风险的关键策略.
- 这些发现强调了早期心血管健康促进对长期孕产妇健康结果的重要性.
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