多民族人口中的不规则工作时间和心血管疾病之间的关联:HELIUS研究
Gilbert W M Wijntjens1, Ali Dehghani1, Ehsan Motazedi1
1Department of Public and Occupational Health, Amsterdam Public Health Research Institute, Amsterdam UMC, Amsterdam, 1100 DD, The Netherlands.
Occupational medicine (Oxford, England)
|October 10, 2025
概括
不规则的工作时间增加了心血管疾病 (CVD) 的风险,并观察到显著的种族差异. 与压力相关的途径调解了这些关联,突出了针对不同人群的有针对性的干预措施的需要.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 职业健康 职业健康 职业健康
背景情况:
- 不规则的工作时间是心血管疾病 (CVD) 的公认危险因素.
- 了解这种风险的种族差异对于公共卫生倡议至关重要.
- 与压力相关的路径可能解释工作时间表和心血管疾病之间的联系.
研究的目的:
- 调查不规则工作时间与心血管疾病之间的关系中的种族差异.
- 探索与压力相关的途径在这个协会中扮演的调解角色.
- 分析不同族群中不规则工作时间的CVD流行率.
主要方法:
- 这是一项针对来自不同种族背景的18284名参与者的横截面研究 (荷兰人,南亚苏里南人,非洲苏里南人,加纳人,土耳其人,摩洛哥人).
- 后勤回归分析,以评估不规则的工作时间和流行心血管疾病 (心肌梗塞,旁路手术,中风) 之间的关联.
- 对行为,生理和心理社会压力进行调整的调解者模型;通过种族来测试相互作用和分层.
主要成果:
- 不规则的工作时间与较高的心血管疾病患病率相关 (OR 1.27).
- 观察到种族和不规则的工作时间在心脏病发病率之间存在显著的相互作用.
- 在南亚苏里南人 (OR 1.47),摩洛哥人 (OR 1.43) 和非洲苏里南人 (OR 1.29) 中发现了最强的关联.
- 在与压力相关的调解途径中发现了实质性的种族差异.
结论:
- 不规则的工作时间与多民族人口中心血管疾病患病率增加有关.
- 在与不规则的工作时间相关的CVD风险中存在种族差异.
- 与压力相关的途径显著调解了不规则工作和心血管疾病之间的关系,因种族而异.
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