恰到好处的适应性干预,以改善艾滋病毒预防和无家可归的年轻人吸毒 (MY-RIDE):随机对照试验的协议
Diane Santa Maria1, Nikhil Padhye1, Michael Businelle2
1Cizik School of Nursing, The University of Texas Health Science Center at Houston, Houston, TX, United States.
JMIR research protocols
|October 10, 2025
概括
这项研究测试了MY-RIDE,这是一项针对无家可归青年的移动干预措施,以减少艾滋病毒风险和物质使用. 结果将显示个性化的实时支持是否能改善预防策略并降低物质使用.
科学领域:
- 公共卫生 公共卫生
- 数字健康干预措施 数字健康干预措施
- 青少年健康 青少年健康
背景情况:
- 无家可归的年轻人面临着更高的艾滋病毒风险和更高的自杀和过量服用死亡率.
- 现有的干预措施往往忽略了实时,可修改的风险因素.
- 恰到好处的适应性干预 (JITAI) 对预防艾滋病毒和药物滥用研究具有前景.
研究的目的:
- 开发和实施一项随机对照试验,用于"激励青年减少感染,脱节和情绪失调" (MY-RIDE) 干预.
- 评估MY-RIDE的有效性,一个JITAI,改善艾滋病毒预防和减少无家可归的年轻人中吸毒.
- 评估MY-RIDE对保护因素和风险先例的影响.
主要方法:
- 一个随机的注意力控制试验,招募了320名年龄在18-25岁的无家可归青年.
- 使用信息-动机-行为技能模型共同设计的干预,包括护士主导的会议和3个月的个性化JITAI消息.
- 参与者将获得带有干预应用程序的智能手机,并可访问按需的护士辅助电话.
主要成果:
- 招聘于2024年秋季启动,迄今为止已有192名参与者注册.
- 基线调查,参与者完成的HIV/STI测试.
- 3,6个月和12个月的后续评估,以衡量干预措施的采用和结果.
结论:
- 该研究将确定MY-RIDE是否能提高艾滋病毒预防策略,并减少与对照组相比的物质使用.
- 评估MY-RIDE对使用暴露前预防 (PrEP) 的意愿和与心理健康/物质使用服务的参与的影响.
- 评估MY-RIDE对压力,物质使用冲动和整体物质使用的影响.
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