帕斯普拉纳视切除术后的眼高血压和视眼:系统性审查和元分析
Gabriele Gallo Afflitto1, Lorenzo Fabozzi2, Filomena Palmieri3
1Ophthalmology Unit, Department of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy; Moorfields Eye Hospital NHS Foundation Trust, London, UK.
Ophthalmology
|October 10, 2025
概括
帕斯普拉纳视切除术 (PPV) 增加了眼睛高血压 (OHT) 和青光眼的风险,特别是在伪眼睛. 透镜状态是改变PPV后风险的关键因素,需要量身定制的手术规划和监测.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼研究研究 玻璃眼研究
- 视网膜外科手术 视网膜外科手术
背景情况:
- 帕斯平面玻璃切除术 (PPV) 是一种常见的玻璃关节疾病的手术程序.
- 人们对PPV对眼内压力 (IOP) 和青光眼的长期影响存在担忧.
- 伪眼睛,缺乏天然透镜屏障,可能会增加风险.
研究的目的:
- 系统地审查和分析PPV后眼高血压 (OHT) 和玻璃眼的风险.
- 调查透镜状况 (phakic vs. pseudophakic) 作为这些风险的修饰者的作用.
主要方法:
- 对比研究 (随机和非随机) 的系统审查和元分析.
- 搜索的主要数据库 (MEDLINE,EMBASE,科学网) 截至2024年5月.
- 使用ROBINS-I评估偏差风险和使用GRADE的证据确定性.
主要成果:
- 包括41个观察性研究 (54,006名患者).
- 聚合后PPVOHT风险为5.6%,玻璃眼风险为3.9%.
- 伪发光眼与发光眼相比,OHT (OR 3.2) 和玻璃眼 (OR 11.8) 的几率明显更高.
结论:
- PPV与临床上显著的OHT和玻璃眼风险有关.
- 镜片状态是影响PPV后风险的关键因素.
- 研究结果支持对接受PPV的患者进行个性化外科规划和警的术后监测.
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