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Updated: Jan 15, 2026

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跨膜域相互作用是NSG1调节sortilin ectodomain脱落的基础

Malene Overby1, Lasse Messell Desdorf2, Lisbeth Kjølbye2

  • 1Department of Clinical Medicine, Translational Neuropsychiatry Unit, Aarhus University, Aarhus, Denmark.

The Journal of biological chemistry
|October 10, 2025
PubMed
概括

神经元特异性蛋白NSG1通过结合其跨膜域来调节索尔提林的分泌. 在sortilin中的特定突变.

关键词:
阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.在NSG1中,NSG1是NSG1.一个ectodomain的流失.蛋白质蛋白质相互作用蛋白质溶解加工是一种蛋白质溶解加工.这种类型的LINK.跨膜领域的相互作用.

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