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Updated: Jan 15, 2026

Advances in Human Induced Pluripotent Stem Cell-Derived Chimeric Antigen Receptor-Expressing Natural Killer Cells
11:08

Advances in Human Induced Pluripotent Stem Cell-Derived Chimeric Antigen Receptor-Expressing Natural Killer Cells

Published on: February 14, 2025

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在肝细胞癌中,VRK2向增强了通过MYC破坏稳定的抗PD-1免疫疗法

Chen Su1,2, Zhibin Liao1,2, Jie Mo1,2

  • 1Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, 430030, Wuhan, Hubei, People's Republic of China.

Nature communications
|October 10, 2025
PubMed
概括

疫苗相关激酶2 (VRK2) 通过酸化稳定肝细胞癌 (HCC) 蛋白MYC,阻止其降解. 抑制VRK2可以减少MYC,抑制瘤,并增强MYC驱动的HCC的免疫疗法.

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Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer06:51

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