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Updated: Jan 15, 2026

Density Gradient Multilayered Polymerization DGMP: A Novel Technique for Creating Multi-compartment, Customizable Scaffolds for Tissue Engineering
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在LARGE1过程中聚合了长度控制的母糖甘在prodystroglycan上.

Soumya Joseph1,2,3, Nicholas J Schnicker2,4, Nicholas Spellmon5

  • 1Senator Paul D. Wellstone Muscular Dystrophy Specialized Research Center, University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA, USA.

Nature communications
|October 10, 2025
PubMed
概括

通过LARGE1合成母糖需要特定的蛋白质域和原料. 这种酶过程性聚合matriglycan,其长度由dystroglycan产域控制,提供治疗潜力.

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