在新加坡进行基于风险的乳腺查的BREATHE队列的个人资料
Peh Joo Ho1,2,3, Jenny Liu1,4, Su-Ann Goh3
1Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, 117549, Singapore.
Scientific reports
|October 10, 2025
概括
针对她的BREAst查量身定制 (BREATHE) 研究试点针对亚洲女性进行个性化乳腺癌查. 基于风险的查是可行的和可以接受的,激励妇女进行早期检测.
科学领域:
- 在瘤学瘤学.
- 预防医学 预防医学
- 公共卫生 公共卫生
背景情况:
- 乳腺癌查计划往往缺乏个性化.
- 多民族的亚洲人口对查方案提出了独特的挑战.
研究的目的:
- 试点一个个性化的,基于风险的乳腺癌查计划.
- 评估亚洲妇女量身定制查的可行性和可接受性.
- 评估乳腺癌风险因素和查行为.
主要方法:
- 针对她的BREAst查量身定制 (BREATHE) 研究招募了4592名年龄在35-59岁之间的女性.
- 数据收集包括人口统计,生活方式,生殖风险,意识,行为,满意度和乳房镜检查结果.
- 还收集了基因型数据,以进行全面的风险评估.
主要成果:
- 高于平均水平的乳腺癌风险随着年龄的增长而增加,在50-59岁的女性中达到42%.
- 参与者重视知道自己的风险,并被激励参加乳房镜检查.
- 该研究表明,在研究期间,随访损失为8.6%.
结论:
- 在亚洲多民族人口中,个性化,基于风险的查计划是可行的和可以接受的.
- 量身定制的查方案可以提高早期发现乳腺癌并改善结果.
- BREATHE研究为个性化癌症查举措提供了有价值的模型.
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