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Updated: Jan 15, 2026

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
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在第三阶段确认性试验中,对缺失数据的多重推算的使用的监管经验

Mouna Sassi-Sayadi1, Pierre Verweij2, Peter Cornelisse2

  • 1Idorsia Pharmaceuticals Ltd, Hegenheimermattweg 91, Allschwil, 4123, Switzerland. Mouna.Sassi-Sayadi@viatris.com.

Therapeutic innovation & regulatory science
|October 10, 2025
PubMed
概括

本研究应用多重推算 (MI) 来处理高血压试验中缺少的数据,解决重复测量混合模型 (MMRM) 的局限性. 监管机构现在期望在初级试验结果中缺失非随机 (MNAR) 分析.

关键词:
MMRM MMRM 是一个MMRM.缺少的数据数据.多重的归咎是多重的归咎.监管机构 监管机构监管互动 监管互动敏感性分析的分析.

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