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Updated: Jan 15, 2026

Injections of Lipopolysaccharide into Mice to Mimic Entrance of Microbial-derived Products After Intestinal Barrier Breach
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Injections of Lipopolysaccharide into Mice to Mimic Entrance of Microbial-derived Products After Intestinal Barrier Breach

Published on: May 2, 2018

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人体肠道细菌产生结构相关的单甘油脂,具有对比的免疫功能

Ji-Sun Yoo1, Da-Jung Jung1, Byoungsook Goh1

  • 1Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston, MA, USA.

Nature microbiology
|October 10, 2025
PubMed
概括

肠道细菌产生免疫调节脂质. Bacteroides fragilis产生BfaGCs,而其他细菌如Enterococcus产生aGDGs,可以阻止NKT细胞激活,影响肠道微生物群.

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Biosynthesis of Lipids

Microbial membranes exhibit remarkable diversity in lipid composition, reflecting evolutionary adaptations to various environmental conditions. The three domains of life—Bacteria, Archaea, and Eukarya—synthesize membrane lipids through distinct biosynthetic pathways, leading to fundamental structural differences that impact membrane stability, function, and adaptability.Fatty Acid-Based Lipids in Bacteria and EukaryaBacteria and eukaryotes share a common fatty acid biosynthesis...
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Formation of Lipopolysaccharides

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