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来自Mycobacterium tuberculosis的林诺酸增加了调节性T细胞功能,以促进巨细胞内的细菌存活

Hongyu Cheng1,2, Shenzhi Li1,2, Hongjie Liu1

  • 1Shanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, People's Republic of China.

Nature microbiology
|October 10, 2025
PubMed
概括

结核菌使用一种代谢物 - - 酸来增加调节性T细胞 (Treg) 并逃避免疫反应. 这一过程涉及Rv1272c,促进巨细胞内的Mtb生存.

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