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Updated: Jan 15, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
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氨皮cillin sulbactam对血清水平的影响相当于piperacillin tazobactam的影响

Sho Tashiro1, Ryota Tanaka2, Ken Shiraiwa2

  • 1Department of Clinical Pharmacy, Oita University Hospital, Yufu, Oita, 879-5593, Japan. tashiros@oita-u.ac.jp.

Scientific reports
|October 10, 2025
PubMed
概括

西林/苏尔巴克坦 (ABPC/SBT) 和皮佩拉西林/塔扎巴克坦 (PIPC/TAZ) 均可显著降低血清水平 (SPL). 风险因素包括基线SPL,治疗持续时间和女性性别. 建议对接受这些抗生素的患者进行仔细的SPL监测.

关键词:
西林 / 苏尔巴克塔姆.贝塔乳酸/贝塔乳酸酶抑制剂组合低血清症是什么情况?皮佩拉西林 / 塔扎巴克坦血清的水平是血清水平.

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