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Updated: Jan 15, 2026

Label-Free Non-Linear Optics for the Study of Tubulin-Dependent Defects in Central Myelin
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Published on: March 24, 2023

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在LMNA心肌病中,微管体力驱动核损伤

Daria Amiad Pavlov1, Julie Heffler2, Carmen Suay-Corredera1

  • 1Department of Physiology, Pennsylvania Muscle Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Nature cardiovascular research
|October 10, 2025
PubMed
概括

微管,而不是LINC复合体,在层层A/C缺陷中损伤细胞核. 破坏这些微管可以防止核损伤并保持心脏功能,为LMNA心肌病提供了一个新的治疗点.

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