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Updated: Jun 29, 2026

Improved Visualization and Quantitative Analysis of Drug Effects Using Micropatterned Cells
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从模拟到应用:通过PBPK建模,加强可溶性微阵列贴片的临床前评估

Maja Railic1, Wilhelmus E A de Witte2, Stephan Schaller2

  • 1SSPC, Research Ireland Centre for Pharmaceuticals, School of Pharmacy, University College Cork, Cork, T12 K8AF, Ireland. 121100335@umail.ucc.ie.

Drug delivery and translational research
|October 10, 2025
PubMed
概括

基于生理学上的药理动力学 (PBPK) 建模通过可溶性微阵列补丁 (MAP) 增强了药物输送. 这种优化的PBPK模型准确地预测了药物动力学,加速了监管批准的临床前开发.

关键词:
临床翻译 临床翻译可以溶解的微阵列贴片.在PBPK建模中使用PBPK模型.临床前评估 临床前评估

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