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功能性消化不良:从人类到狗,对29个案例进行了回顾性研究,说明了一个复杂的实体
Hugo Kaufmann1, Henri Duboc2, Valérie Freiche3,4
1Service de médecine interne, Centre Hospitalier Vétérinaire Frégis - IVC Evidensia France, Gentilly, France. hugokaufmann@outlook.fr.
BMC veterinary research
|October 11, 2025
概括
功能性消化不良 (FD) 是一种新发现的狗胃肠道疾病,表现为慢性吐和无有机原因的不适. 许多狗通过量身定制的治疗显著改善,这表明肠-大脑轴链接.
科学领域:
- 兽医胃肠病学 兽医胃肠病学
- 狗内科 狗内科 狗内科
背景情况:
- 像功能性消化不良 (FD) 这样的功能性胃肠道疾病 (FGID) 在人类中很常见.
- 狗的FD,其特征是没有有机原因的上部胃肠道症状,以前没有报告过.
- 本研究描述了疑似犬类FD的临床表现.
研究的目的:
- 提供疑似犬功能性消化不良症的全面描述.
- 为了确定患有FD的狗的临床症状,信号和诊断结果.
- 评估治疗结果和探索潜在的潜在机制.
主要方法:
- 追溯29只疑似FD的狗的案例系列.
- 包括所需的临床症状与标准诊断结果 (血液检查,成像,内镜,组织病理学) 不一致.
- 收集的数据包括信号,临床症状,诊断结果,治疗和随访.
主要成果:
- FD主要影响雌性狗 (66%),并与吐 (97%),腹痛 (58%) 和pica (52%) 相关.
- 症状的平均持续时间为1.5年,平均发病年龄为1.5岁.
- 76%的狗通过包括饮食改变,抗酸药和前动力学药在内的治疗得到改善;主人焦虑是常见的报告.
结论:
- 狗FD是一种新兴的功能性胃肠道疾病,特别是在小,中年雌性狗中.
- 它表现为慢性胃肠道不适和吐,老板经常报告焦虑.
- 狗FD可能涉及肠-大脑轴障碍,并保证将其纳入难治性上部消化系统问题的差异诊断中.
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