患者对风险评估和缓解策略的看法和经验
Ameet Sarpatwari1, Su Been Lee1, Heidi Zakoul1
1Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
患者了解风险评估和缓解策略 (REMS) 药物风险,但面临着处方医生的访问和行政负担的挑战. 改善护理协调和患者参与可以提高REMS计划的有效性.
科学领域:
- 药物监督 药物监督 药物监督
- 医疗保健服务研究 医疗服务研究
- 患者体验 患者体验
背景情况:
- 风险评估和缓解战略 (REMS) 计划是FDA授权的干预措施,以管理药物风险.
- 这些计划需要具体的行动,如患者教育和实验室测试.
- 了解患者和护理人员的观点对于优化REMS有效性至关重要.
研究的目的:
- 探索患者和护理人员对REMS程序的看法和经验.
- 识别REMS实施中的挑战和促进者,并提供确保安全使用的要素.
- 收集改善REMS程序设计和交付的见解.
主要方法:
- 对135名使用特定高风险药物的患者或病人的护理人员进行了半结构面试.
- 参与者使用了阿姆图祖马布,安布里森坦,克洛扎平,异丁,莱纳利多米德,佩格瓦利或氧酸盐.
- 招聘使用了患者登记,社交媒体和支持小组.
主要成果:
- 患者表现出对REMS风险和要求的了解.
- 报告说,在寻找处方者方面存在困难,特别是对于克洛扎.
- 行政负担造成了丧,通过护理协调来减轻.
- 怀孕和克洛扎平的测试带来了情感和后勤方面的挑战.
- 参与者希望在REMS材料之外进行更广泛的风险沟通.
结论:
- 虽然患者对REMS有所了解,但需要在系统层面进行改进.
- 解决处方医生的准入,行政负担和护理协调问题可以增强REMS.
- 对所有药物风险进行改善的患者参与和沟通至关重要.
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