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Updated: Jan 15, 2026

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
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Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Published on: April 4, 2018

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非编码重复扩展与帕金森病风险的关联:来自英国生物库全基因组测序研究的证据

Zhen Hu1, Qin-Qin Yan2, Jing-Jin Wan3

  • 1Department of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Movement disorders : official journal of the Movement Disorder Society
|October 11, 2025
PubMed
概括

这项研究研究了帕金森病 (PD) 风险中的核酸重复扩张. 病原性C9ORF72重复名义上与PD风险增加有关,而FMR1重复可能提供保护.

关键词:
帕金森病的疾病.非编码重复扩展的重复扩展.整个基因组测序的测序.

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