淋巴扩散性恶性瘤患者的核心针活检:一个观察性单中心队列研究
Blas Holger Mogensen1, Torsten Holm Nielsen1,2, Mette Ølgod Pedersen3,4
1Department of Hematology, Zealand University Hospital, Roskilde, Denmark.
European journal of haematology
|October 11, 2025
概括
核心针活检 (CNB) 对于淋巴瘤诊断来说不那么侵入性,但诊断产量 (74%) 比外科切除活检 (SEB) (98%) 低. 需要改进,以提高CNB的准确性,以获得更好的临床效用.
科学领域:
- 在瘤学瘤学.
- 病理学 病理学 病理学
- 诊断成像 诊断成像 诊断成像
背景情况:
- 核心针活检 (CNB) 和外科切除活检 (SEB) 是用于淋巴瘤诊断的标准.
- 欧洲央行是黄金标准,但中国央行提供了一个不那么侵入性,成本效益较低的替代方案.
- 有关CNB的诊断产量存在担忧.
研究的目的:
- 在常规临床实践中,用于淋巴瘤诊断,评估与SEB相比,CNB的诊断性能.
- 确定影响CNB准确性的因素.
主要方法:
- 对179名新诊断为淋巴瘤的患者进行了回顾性研究.
- 在CNB (n=84) 和SEB.之间对诊断产量和准确性的比较.
- 对活检位置,淋巴瘤亚型和组织体积对CNB结果的影响的分析.
主要成果:
- 确定的淋巴瘤诊断在74%的CNB病例中实现,而SEB的病例为98%.
- 根据活检部位,淋巴瘤亚型和组织体积,CNB准确度有显著差异.
- 不确的诊断更常见于惰性淋巴瘤和有限的组织样本.
结论:
- 对于淋巴瘤诊断,CNB的诊断收益率低于SEB.
- 活检位置,淋巴瘤亚型和样本充分性是影响CNB准确性的关键因素.
- 虽然安全,但CNB需要改进技术和改进患者选择,以提高其诊断效用.
更多相关视频
06:03Use of Electromagnetic Navigational Transthoracic Needle Aspiration E-TTNA for Sampling of Lung Nodules
Published on: May 23, 2015
22.8K
06:42Optimization of Breast Biopsy and Mastectomy Sample Collection Procedures for Biobanking, Personalized Medicine, and Research Applications
Published on: September 2, 2025
409
相关概念视频
Bone Marrow Sampling and Transplants
881
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
881
Primary Lymphoid Organs
14.6K
Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
14.6K
