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Updated: Jan 15, 2026

Mapping Alzheimer's Disease Variants to Their Target Genes Using Computational Analysis of Chromatin Configuration
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整合全基因组和整个表观基因组的关联,用于抗精神病诱导的外皮拉米德副作用

Kai Yao1, Johan H Thygesen2, Siobhan K Lock3

  • 1Molecular Psychiatry Laboratory, Division of Psychiatry, University College London, Rockefeller Building, 21 University Street, London, WC1E 6BT, UK.

Psychopharmacology
|October 11, 2025
PubMed
概括

遗传因素会影响抗精神病药物的副作用. 这项研究在精神分裂症患者中发现了与超金字塔副作用 (EPSE) 相关的新型遗传关联和甲基化变化,为生物学机制提供了洞察力.

关键词:
这是一种抗精神病药物.整个表观基因组的关联.外皮拉米德的副作用全基因组的关联.精神分裂症是一种精神分裂症.

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