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Updated: Jan 15, 2026
10:34
A High-content Assay for Monitoring AMPA Receptor Trafficking
Published on: January 28, 2019
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全球AMPA受体研究的热点和趋势 (2000-2025):一个图书统计和可视化分析
Yunsheng Liu1, Rongde Zhong2, Xianlin Wu1
1Cancer Center, Shenzhen Hospital (Futian) of Guangzhou University of Chinese Medicine, Futian District, No. 6001, Beihuan Avenue, Shenzhen City, 518000, China.
Naunyn-Schmiedeberg's archives of pharmacology
|October 11, 2025
概括
本文献分析显示,AMPA受体 (AMPAR) 研究已经从基本特性演变为疾病应用. 关键趋势显示,神经和精神疾病的转变,指导未来的治疗策略.
科学领域:
- 神经科学是一个神经科学.
- 药理学 药理学是指药理学的学科.
- 图书统计学 图书统计学
背景情况:
- AMPA受体 (AMPARs) 对突触功能至关重要,并与神经系统疾病有关.
- 从2000年开始对AMPAR研究进行全面的文献分析是缺乏的.
研究的目的:
- 系统地分析2000年至今的AMPAR研究趋势.
- 识别关键贡献者,有影响力的出版物和新兴研究热点.
- 引导未来在AMPAR相关神经科学和治疗方面的研究.
主要方法:
- 对来自Web of Science,PubMed和Scopus的37,000篇论文进行了图书统计分析.
- 使用CiteSpace,VOSviewer和Bibliometrix进行数据分析.
- 审查的出版成果,国家/机构贡献,期刊影响,作者生产力和关键词的同时出现.
主要成果:
- 美国领先于出版量和引用量;Huganir RL是被引用最多的作者.
- 顶级期刊包括神经科学杂志和神经元.
- 研究热点从AMPAR特性演变为疾病关联 (阿尔茨海默氏症,抑郁症) 和治疗方法.
结论:
- AMPAR研究已经从基础神经生理学转向翻译应用.
- 人们越来越重视神经和精神疾病.
- 未来的研究应该专注于本地AMPAR复合物,贩运和精确疗法,需要跨学科的合作.
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