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艾弗梅克丁是否会污染猪场周围的环境?
Alicia Maria Carrillo Heredero1, Elena Butovskaya2, Giulia Segato2
1Department of Veterinary Sciences, University of Parma, Parma, Italy.
Veterinary medicine and science
|October 11, 2025
概括
在养猪场使用伊弗梅克会导致环境污染,其残留物在土壤中发现,并在便中根据施用而变化. 这突显了对非目标物种的风险,以及需要可持续的药物管理.
科学领域:
- 环境科学 环境科学
- 兽医药理学 兽医药理学
- 生态毒理学 生态毒理学
背景情况:
- 药品,包括像ivermectin这样的宏环乳,越来越多地被认为是环境污染物.
- 在密集畜牧业中广泛使用ivermectin引发了人们对其持续性和环境影响的担忧.
研究的目的:
- 调查意大利密集养猪场便和环境样本中的ivermectin残留物.
- 分析服药方式 (口服与注射) 对ivermectin分泌模式的影响.
- 评估与土壤和水中的ivermectin污染相关的潜在环境风险.
主要方法:
- 从猪便,泥,土壤和废水中收集样本,这些样本来自两家用ivermectin处理的农场和一家对照农场.
- 使用液体染色学-并联质谱法 (LC-MS/MS) 分析ivermectin残留物.
- 在不同时间点 (治疗前,治疗后1天,治疗后10天) 的残留物水平的比较,并按施用途径进行比较.
主要成果:
- 与注射 (中位数14.84μg kg-1) 相比,口服后立即便便便中的ivermectin度显著更高 (中位数930.25μg kg-1).
- 被注射的母猪在治疗后10天显示出更高的便残留物,这表明分泌动态不同.
- 在肥田中检测到土壤污染ivermectin,其度高达39.23μg kg-1,可能超过土壤无脊椎动物的生态毒理学值.
结论:
- 在养猪场中使用ivermectin有助于环境污染,特别是土壤污染.
- 排泄模式和环境残留物含量根据ivermectin的施用途径有很大差异.
- 可持续的药物管理实践对于减轻与牲畜中ivermectin使用相关的生态风险至关重要.
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