伊索巴巴可以通过GPR35-NLRP3信号缓解高尿血症引起的骨损失

Xiaolin Cen1, Suiqing Mai1, Rongrong Huang1

  • 1Office of Clinical Trial of Drug, Guangdong Provincial Key Laboratory of Bone and Joint Degeneration Diseases, The Third Affiliated Hospital of Southern Medical University, Guangzhou, 510630, China.

概括

伊索巴巴 (IBC) 是一种GPR35激动剂,通过通过GPR35-NLRP3通路增强骨质基因分化,防止高尿血症诱导的骨质损失. 这使IBC成为高尿血症患者骨质疏松症的潜在治疗方法.

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