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微脉冲与连续波跨膜二极管环光凝固在治疗青光眼瘤中的有效性和安全性

A Gaulier¹, B Vabres¹, C Cornée¹

¹Ophtalmology Department, Nantes University Hospital, 16, allée Jacques-Berque, 44000 Nantes, France.

Journal francais d'ophtalmologie

|October 11, 2025

概括

传统的穿细胞循环光凝血 (CW-TSCP) 提供了更大的眼内压力降低和更少的药物需求,而不是微脉冲二极管激光 (MPTLT) 治疗青光眼. 然而,CW-TSCP具有更高的持续性低血压的风险.

科学领域:

眼科医生眼科眼科
医疗技术医疗技术医学技术
青光眼治疗方法青光眼治疗方法

背景情况:

眼管理需要有效的眼内压力 (IOP) 降低.
跨膜环光凝结技术用于治疗耐火性玻璃眼.
比较传统的穿细胞循环光凝血 (CW-TSCP) 和微脉冲二极管激光穿细胞循环光凝血 (MPTLT) 对于优化患者的治疗结果至关重要.

研究的目的:

为了比较CW-TSCP与MPTLT在青光眼患者中的疗效和耐受性.
为了评估两种激光治疗之间的IOP降低,药物使用和并发症率.
为了确定这些青光眼干预措施的长期有效性.

主要方法:

一个单一中心的回顾性研究包括在2018年1月至2020年12月期间接受CW-TSCP或MPTLT治疗的患者.
收集的数据包括IOP,青光眼药物和多次随访间隔 (1-24个月) 的并发症.
成功被IOP目标 (6-21mmHg或≥20%降低) 定义为稳定或减少药物使用,没有进一步的手术.

主要成果:

在16个月的中位数随访后,69%的CW-TSCP眼睛和54%的MPTLT眼睛满足了成功标准.
CW-TSCP显示了显著更大的平均IOP降低 (8.0mmHg对2.1mmHg) 和药物降低 (1.24对0.6).
与MPTLT (2%) 相比,CW-TSCP (8%) 的持续性低血压更频繁.

结论:

无论是CW-TSCP还是MPTLT,都有效地降低了长期的IOP.
CW-TSCP提供了更实质性的IOP和药物减少,但具有较高的低血压风险.
需要进一步的随机试验来确认CW-TSCP的卓越疗效和评估耐受性.

关键词:

循环二极管是指循环二极管.眼光障碍症眼光障碍症眼光障碍症眼光障碍眼光障碍眼光障碍眼光障碍激光微脉冲的跨细胞激光器微脉冲跨的激光治疗方法

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