CircPFKP编排了一种新的竞争性内源RNA网络,以调节SPRY4/p38-MAPK信号传输,并调节乳头甲状腺癌的攻击性

Nizhen Xu1, Mingjie Zheng2, Chu Zhu3

  • 1Department of Thyroid and Head & Neck Surgery, Institute of Micro-Invasive Surgery of Zhejiang University, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.

概括

循环RNAs (circRNAs) 在乳头甲状腺癌 (PTC) 进展中发挥作用. 沉默circPFKP通过调节miR-4516和SPRY4来抑制PTC细胞的生长和扩散,提供了一个潜在的治疗标.

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