从1990年到2021年,对中风和亚型负担的年龄周期队列分析
Dengpan Song1, Ruoyu Cai2, Yan Du1
1Department of Neurosurgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Nutrition, metabolism, and cardiovascular diseases : NMCD
|October 11, 2025
概括
从1990年到2021年,全球中风发病率和死亡率下降,但总病例增加. 策略必须适应区域差异,重点关注老年人中风护理和中年人脑下关节出血.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 神经学 神经学
背景情况:
- 脑卒中是一个重大的全球健康挑战,导致大量的发病率和死亡率.
- 了解中风发病率和死亡率的长期趋势对于有效的公共卫生干预至关重要.
研究的目的:
- 分析从1990年到2021年中风发病率和死亡率的32年全球趋势.
- 检查不同社会人口统计指数 (SDI) 地区的这些趋势.
- 调查年龄,月经和出生队伍对中风模式的影响.
主要方法:
- 利用了2021年全球疾病负担 (GBD) 数据库.
- 应用了年龄周期队列 (APC) 模型来估计缺血性中风 (IS),脑内出血 (ICH) 和脑下出血 (SAH) 的发病率和死亡率的变化.
- 计算了中风亚型的净漂移,局部漂移和周期/队列效应.
主要成果:
- 在1990年至2021年期间,IS,ICH和SAH的全球发病率和死亡率下降,尽管总病例总量总体上升.
- 在IS (-0.52%的发病率,-1.47%的死亡率),ICH (-1.41%的发病率,-1.64%的死亡率) 和SAH (-1.31%的发病率,-2.77%的死亡率) 中观察到显著的年均百分比下降.
- 年龄影响增加,而周期和队列效应减少;IS负担在高SDI地区更高,而ICH和SAH在低SDI地区更普遍.
结论:
- 针对不同的全球地区,定制的中风管理策略是必不可少的.
- 建议对老年人群进行加强的中风护理.
- 在中年人群中,应特别注意甲状腺下部出血.
相关概念视频
Regulation of Stroke Volume
4.7K
The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
4.7K
Prevalence and Incidence
1.5K
In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
1.5K
Cardiac Output II: Effect of Stroke Volume on Cardiac Output
3.1K
Cardiac output (CO), the amount of blood the heart pumps per minute, is a parameter in cardiovascular physiology determined by stroke volume and heart rate. Stroke volume, the amount of blood pushed from one of the ventricles per heartbeat, is influenced by preload, afterload, and contractility.
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...
3.1K
Ischemic Heart Disease: Overview
2.9K
Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
2.9K
Cardiac Output and Stroke Volume
4.4K
Cardiac output (CO) is an integral aspect of human physiology, reflecting the heart's efficiency and responsiveness to the body's needs. It represents the volume of blood that the left or right ventricle ejects into the aorta or pulmonary trunk each minute. The CO is calculated by multiplying the heart rate (HR)—the number of heartbeats per minute—by the stroke volume (SV)—the amount of blood pumped out with each heartbeat.
In an average resting adult male, the typical cardiac...
In an average resting adult male, the typical cardiac...
4.4K
Aneurysm II: Clinical Manifestations and Diagnostic Studies
293
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
293


